Antibodies to Hepatitis A Virus (HAV) IgM ELISA Test Kit

For in vitro diagnostic and professional use only.

PRODUCT NAME

Anti-HAV IgM ELISA Test Kit (Serum/Plasma)

INTENDED USE

This kit is a qualitative detection of human serum/plasma of hepatitis A virus IgM. The kit is suitable for clinical screening and diagnosis of hepatitis A virus infection in serum/plasma.

TEST PRINCIPLE

Hepatitis A virus (HAV) is a kind of RNA virus, which belongs to the family of Picornavirus. HAV showed a spherical particles shape with 27 nm in diameter, icosahedral symmetry consisted of 32 shell particles, containing linear single-strand RNA. Hepatitis A is a kind of intestinal infectious disease caused by hepatitis A virus (HAV) with a worldwide distribution. Children and adolescents are most likely to be infected, and the peak incidence is in winter and spring. Hepatitis A is the most common type of acute viral hepatitis, mainly spread by fecal-oral route. The incubation period of hepatitis A virus is 15 to 45 days, HAV-IgM antibody can be detected in serum/plasma a short time later after infected, continue to rise very rapidly, peaking in about 2 weeks, decreasing gradually, disappear in 8 weeks. While HAV-IgG antibody appear later than IgM and will persistent for a long time. Detection of HAV- IgM antibody can diagnose HAV infection in early stage for its simple, fast, and high specificity.

This kit uses capture ELISA principle to detect HAV IgM. Purified anti-human IgM antibody is pre-coated on the microplate, the HAV IgM in sample will combine with anti-human IgM first, then combine with enzyme-labeled anti-HAV-HAV antigen complex, and shows blue color in the microplate. This kit is used for the specific detection of HAV IgM antibody in human serum/plasma.

COMPONENTS