Product Details:
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Sample Type: | Serum, Plasma | Storage Temperature: | 2-8°C |
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Sensitivity: | High | Format: | Kit |
Product Name: | Elisa Test | Test Type: | ELISA |
Specificity: | High | Shelf Life: | 18 Months |
Highlight: | Accurate Detection ELISA KITS,High Performance ELISA KITS,Sensitive Detection ELISA KITS |
Human epididymis protein 4 (HE4) belongs to the family of whey acidic four disulfide core (WFDC) proteins with suspected trypsin inhibitor properties. Other proteins in this family include SLPI, Elafin, and PS20 (WFDC1). The HE4 gene codes for a 13kD protein, although in its mature glycosylated form the protein is approximately 20-25 kD, and consists of a single peptide containing two WFDC domains. HE4 was first identified in the epithelium of the distal epididymis and originally predicted to be a protease inhibitor involved in sperm maturation. HE4 has since been reported to be expressed in several normal tissues including epithelia of respiratory and reproductive tissues and also in ovarian cancer tissue. In addition to expression on a cellular level, secreted HE4 has been detected in high levels in the serum of ovarian cancer patients. In a case/control study comparing patients with ovarian cancer to healthy and benign conditions, Hellström et al. found that HE4 detected ovarian cancer with 67% sensitivity at a specificity level of 96%. In a subsequent study evaluating numerous known biomarkers for ovarian cancer, HE4 showed the highest sensitivity for the detection of ovarian cancer, particularly in early stage disease. In this study, the combination of HE4 and CA 125 was a more accurate predictor of malignancy than either marker alone, with a sensitivity of 76% and a specificity of 95%. Ovarian cancer is the fourth most common cause of cancer-related death in women worldwide. To improve the triage of patients presenting with pelvic mass, the HE4 ELISA may be used in conjunction with CA125 assay as an aid in estimating the risk that the patient is harboring epithelial ovarian cancer. The results must be interpreted in conjunction with other methods in accordance with standard clinical management guidelines. An additional use of the HE4 ELISA is as an aid in monitoring response to therapy for patients with invasive epithelial ovarian cancer. The results should be used in conjunction with other clinical methods used for monitoring ovarian cancer
Our ELISA Diagnostic Test Kit for Infectious Diseases is perfect for various applications and scenarios, including:
The HE4 assay is an enzyme-linked immunosorbent assay (ELISA) for the in vitro quantitative determination of Human Epididymis Protein 4 (HE4) in human serum. It is further intended to be used in conjunction with CA125 as an aid in estimating the risk of epithelial ovarian cancer in premenopausal and postmenopausal women presenting with pelvic mass.
The Elisa Test Kit is a diagnostic tool for detecting the presence of antibodies or antigens in a sample. Our product technical support and services include:
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Frequently Asked Questions for Biovantion BVTE0097 Elisa Test Kit:
Q: What is the place of origin for Biovantion BVTE0097 Elisa Test Kit?
A: The Biovantion BVTE0097 Elisa Test Kit is made in China.
Q: What is the certification for Biovantion BVTE0097 Elisa Test Kit?
A: The Biovantion BVTE0097 Elisa Test Kit is certified with ISO13485.
Q: What is the minimum order quantity for Biovantion BVTE0097 Elisa Test Kit?
A: The minimum order quantity for Biovantion BVTE0097 Elisa Test Kit is 10.
Q: What is the packaging detail for Biovantion BVTE0097 Elisa Test Kit?
A: The Biovantion BVTE0097 Elisa Test Kit is packaged in cartons.
Q: What are the payment terms for Biovantion BVTE0097 Elisa Test Kit?
A: The payment terms for Biovantion BVTE0097 Elisa Test Kit is TT 100% payment.
Q: What is the supply ability for Biovantion BVTE0097 Elisa Test Kit?
A: The supply ability for Biovantion BVTE0097 Elisa Test Kit is 100,000.
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